What is the project about?

VitaDAO, a decentralized autonomous organization, introduces VITA-FAST, an innovative funding model for longevity research. Leveraging the Ethereum blockchain, VITA-FAST are ERC-20 tokens, signifying fractional ownership of the Intellectual Property Non-Fungible Token (IP-NFT) from longevity research conducted at the Korolchuk Lab, Newcastle University. VITA-FAST token holders gain governance rights over the IP, democratizing the decision-making processes in scientific research.

1. What is the project about?

The project is focused on discovering and developing therapeutic compounds that can reactivate autophagy in Npc1 -/- cells. This involves screening bioactive and commercial small molecules in cell survival assays to identify potential autophagy activators that are not cytotoxic. The project uses advanced techniques like luciferase-p6 clearance and Halo-GFP-LC3 orthogonal assays for this purpose.

2. What makes your project unique?

The project's uniqueness lies in its approach to identifying novel compounds that can induce autophagy in NPC1 -/- cells, a crucial process for treating Niemann-Pick Type C disease. Unlike existing treatments, this project employs high-throughput screening methods and innovative assays to discover compounds with high chemical variability and no similarity to existing autophagy inducers, opening up possibilities for new iIP.

3. History of your project.

The project, led by Dr. Korolchuk and his team at Newcastle University, has progressed from generating data on thousands of compounds using advanced screening assays to identifying lead compounds with potential autophagic properties. It has evolved to include the synthesis of derivatives of these compounds and is now moving towards drug translation processes, including pharmacokinetics and scalability studies.

4. What’s next for your project?

The next steps involve screening third-generation compounds, conducting in vitro and in vivo models using patient

Molecules of Korolchuk IP-NFT

ether.fi

Andy

Super Trump Coin

LayerZero

Bitcoin

Pixelverse

DexCheck AI

Solana

Ethereum

Shiba Inu

Pepe

Notcoin

LandWolf (SOL)

Orange

Turbo

Dogecoin

Kaspa

Toncoin

Bonk

Niza Global

PeiPei (ETH)

Bullish CDP LHS1 May Campaign

Bitget CDP LHS1 July Messi Campaign

Big Time - CDP LHS2 (Desktop Only) 2024

Uphold CDP LHS2 May campaign

Bc.game CDP LHS2 July campaign

Bullish Search Bar Banner

DexCheck Community Panel

Solidus AI Banner

Bitmart CDP Community banner

Bullish Portfolio Page Banner

Greed

Extreme fear

Fear

Neutral

Extreme greed

♻️ Rehypothecated

 🔥 Memes

 🔥 Solana Eco

 🔥 AI

🔥 Gaming

🔥 RWA

🔥 PolitiFi

Molecules of Korolchuk IP-NFT pris
VITA-FAST

Molecules of Korolchuk IP-NFT community

Nyheter om Molecules of Korolchuk IP-NFT

Om Molecules of Korolchuk IP-NFT

Mest besøkte kryptovalutaer

Populært